It makes me even more sick when ever I tried it on rough days. The onl thing that ever worked for me was Transderm Scop. It is a prescription bandaid that you put behind your ear and it releases medicine. It is really worth trying it. Any doctor will prescribe it. The only side effect is it gives you dry mouth, but when your in the heat its a good thing to drink more.
Throw a couple Ginger Ale's in the cooler. I will help and better than nothing if you tend to get seasick. (however...if taking friends that think $10 is a fair contribution for the day's fuel...take them out for a seafood dinner the night before...built-in chum churs the next day).
dramamine is an antihistamine. motion sickness is caused by the disruption of the fluid balance in your inner ear (from the rocking motion of a boat, or plane turbulence) that normally tells your brain what is up, what is down, and allows you to maintain your equilibrium, and the visual disorientation caused by the constant, irregular movements of the craft. basically, antihistamines dry out your bodily fluids (hence, the dry mouth), thereby minimizing the fluid disturbances in your inner ear (theoretically). the effectiveness of antihistamines for motion sickness is hit or miss, depending on the person. if you choose to take dramamine, take it one hour before departing. drowsiness and dry mouth are common side effects. drink plenty of fluids (not beer).
as mentioned above, transderm scop (scopalamine) is far more effective in the prevention of motion sickness, and has a more complex mechanism of action. side effects include primarily dry mouth, but drowsiness can occur in some, but is not common.
i've logged approximately 10,000 miles crossing the gulf of mexico delivering boats from galveston to puerto adventuras, mexico, and the florida coast, and i have only come close to getting seasick once - in six hours of 10-foot seas - while wearing the scopalamine patch. i highly recommend them.
ginger ale (and any other products containing ginger) seem to be very effective in easing the nausea associated with seasickness.